Tell your healthcare provider if you have any side effects that bother you or do not go away. These are not all the possible side effects of Botox.
RADIESSE® and RADIESSE® (+) are dermal fillers that are used for smoothing moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases that extend from the corner of your nose to the corner of your mouth).
These are biological products that have already been approved by the FDA, against which biosimilar products are compared. There are 2 for Botox.
It is not known if onabotulinumtoxinA passes into breast milk. Talk to your healthcare provider about the best way to feed your baby.
Based on animal data, onabotulinumtoxinA may harm your unborn baby. Talk to your healthcare provider about the risks of receiving this medicine during pregnancy.
Each dose is injected to a depth of approximately 2 mm and at a 45° angle to the skin surface, with the bevel side up to minimize leakage and to ensure the injections remain intradermal.
After the injections are given, the saline used for bladder wall visualization should be drained. The patient should be observed for at least 30 minutes post-injection.
Tell your health care provider if you have any diseases, injuries or disabilities of the hand, if you have a history forming large, raised scars or if you have had any other skin treatments such as skin peels.
The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults treated for spasticity and other conditions, particularly in those patients who have an underlying condition that would predispose them to these symptoms. In unapproved uses and in approved indications, cases of spread of effect have been reported at doses comparable to those used to treat cervical botox dystonia and spasticity and at lower doses [see Warnings and Precautions (5.1)].
You should minimize strenuous activity and avoid extensive sun or heat exposure for about 24 hours after treatment and until any swelling or redness has resolved.
Your healthcare provider will tell you how often you will receive your injection of Botox. Botox Cosmetic injections should be spaced at least 3 months apart.
Speak to your doctor about how drug interactions should be managed. Botox interacts with just over 110 different medications. Common medications that may interact with Botox include:
The initial dose for a patient without prior use of BOTOX should be at a lower dose, with subsequent dosing adjusted based on individual response. Limiting the Completa dose injected into the sternocleidomastoid muscle to 100 Units or less may decrease the occurrence of dysphagia.
WARNING: DISTANT SPREAD OF TOXIN EFFECT Postmarketing reports indicate that the effects of BOTOX and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These may include asthenia, generalized muscle weakness, diplopia, ptosis, dysphagia, dysphonia, dysarthria, urinary incontinence and breathing difficulties. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death.